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Chlamydiae are a group of intracellular organisms closely related to Gram negative bacteria. They grow in eukaryotic cells causing a wide range of diseases in humans, birds and animals.
This species is the most important human pathogen amongst the chlamydiae. There are numerous serotypes causing ocular, respiratory and genital illnesses. The challenge of chlamydial control is the identification of asymptomatic individuals to prevent its spread in the community. Screening has been shown to reduce the prevalence of C. trachomatis and is more cost-effective than treating the sequelae of the disease. Detection of C. trachomatis can be made using the Cellabs monoclonal antibody-based direct immunofluorescence assay (Chlamydia Cel).
This organism causes significant acute respiratory infections in humans, accounting for 10 % of community-acquired pneumonia and 5% of pharyngitis, bronchitis and sinusitis. The infection can be severe in children and the elderly. Detection of C. pneumoniae may be made using the Cellabs monoclonal antibody-based indirect immunofluorescence assay (Chlamydia Cel Pn).
The species of Chlamydia psittaci has a wide host range in most birds and animals. There are over 50 strains found in about 130 bird species, including parrots, pigeons, doves and ostriches. Avian chlamydios also causes acute or chronic disease in poultry, cattle, sheep, and goats resulting in abortion, arthritis and pneumonitis, leading to commercial losses in the meat industry. Transmission of C. psittaci from birds to humans causes psittacosis (ornithosis) resulting in severe pneumonia. Chlamydia pecorum is a species established in 1992. It consists of bovine, ovine and swine strains formerly classified as C. psittaci. Clinical infections involve the central nervous, respiratory and digestive systems. Many animals remain carriers after recovery.
Chlamydia Group Lipopolysaccharide (LPS) Chlamydia Group LPS can be found in all species of Chlamydia, including those listed above.Cellabs provides a monoclonal antibody-based direct immunofluorescence assay (Chlamydia Cel LPS) for the detection of Chlamydia Group LPS.